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Scientist - Antibody & Nanobody Drug Discovery - Job Opportunity at ETH Zürich

Basel, Switzerland
Full-time
Mid-level to Senior
Posted: March 25, 2025
On-site
CHF 90,000 - 120,000 per year based on Swiss academic research sector standards and role complexity

Benefits

Access to cutting-edge research facilities and equipment
Opportunity to work on translational science projects
Collaboration with academic and industry experts
Intellectual property development exposure
Career development in therapeutics research
Association with prestigious ETH Zürich institution

Key Responsibilities

Lead antibody and nanobody discovery projects from concept to preclinical stage
Design and execute protein engineering experiments for therapeutic optimization
Develop and validate cell-based assays for therapeutic assessment
Drive collaborative innovation with interdisciplinary teams
Contribute to technology transfer and IP strategy
Advance therapeutic pipeline development

Requirements

Education

Master's degree or PhD in Biotechnology or related field

Experience

Not explicitly specified but implies 3-5 years based on role complexity

Required Skills

Protein engineering Protein purification Fluorescent microscopy Flow cytometry Cell sorting ELISA and BLI assays Display assays (phage, yeast, or ribosome) Mammalian cell culture Excellent interpersonal skills Creative thinking Project management
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Industry Trends

Increasing focus on nanobody-based therapeutics as next-generation treatment modalities Growing demand for targeted protein-based drugs in personalized medicine Rising importance of translational research in academic institutions Trend toward academic-industry partnerships in drug development

Role Significance

Likely part of a specialized research group of 5-10 scientists within larger department structure
Strategic individual contributor role with potential for project leadership and significant impact on therapeutic development pipeline

Key Projects

Novel antibody therapeutic development programs Platform technology development for drug discovery Preclinical candidate optimization projects Technology transfer initiatives

Success Factors

Deep expertise in protein engineering and characterization techniques Ability to bridge fundamental research with practical therapeutic applications Strong project management skills in translational research context Collaborative approach to interdisciplinary work

Market Demand

High demand due to expanding biotherapeutics market and limited specialist expertise in nanobody development

Important Skills

Critical Skills

Protein engineering expertise critical for therapeutic development Display technology experience essential for drug discovery process Cell-based assay development crucial for therapeutic validation

Beneficial Skills

Experience with regulatory requirements Animal experimentation background Project management capabilities IP development understanding

Unique Aspects

Rare combination of academic research freedom with translational focus
Direct involvement in potential spinoff opportunities
Access to both academic and industry networks
Position in Basel's renowned biotech ecosystem

Career Growth

2-4 years in role before advancement, depending on project success and organizational growth

Potential Next Roles

Senior Scientist in Biotech Industry Group Leader in Academic Research Principal Scientist in Pharmaceutical Company Technical Director in Startup

Company Overview

ETH Zürich

ETH Zürich is one of the world's leading technical and research universities, consistently ranked among top global institutions

Premier academic institution with strong industry connections and significant research funding
Major presence in Swiss biotech ecosystem, particularly in Basel's pharmaceutical hub
Academic excellence-driven environment with strong focus on innovation and practical application
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